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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PMS1
All Species:
13.03
Human Site:
S805
Identified Species:
26.06
UniProt:
P54277
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54277
NP_000525.1
932
105830
S805
D
D
Q
R
Y
S
G
S
T
Y
L
S
D
P
R
Chimpanzee
Pan troglodytes
XP_515987
1061
120272
S934
D
D
Q
R
Y
S
G
S
T
Y
L
S
D
P
R
Rhesus Macaque
Macaca mulatta
XP_001103074
831
93641
K720
T
A
N
G
F
K
I
K
L
I
P
G
V
S
I
Dog
Lupus familis
XP_536002
930
105612
S803
D
D
Q
R
Y
S
G
S
T
Y
L
S
D
P
R
Cat
Felis silvestris
Mouse
Mus musculus
P54279
859
95207
F748
E
I
F
R
K
N
G
F
D
F
V
I
D
E
D
Rat
Rattus norvegicus
NP_001009535
919
103710
S792
V
E
E
R
C
R
G
S
V
Y
L
C
D
P
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507554
871
92244
P756
F
H
H
L
A
D
I
P
R
A
A
E
P
D
L
Chicken
Gallus gallus
NP_001006508
916
103017
L787
D
Y
Q
G
L
N
G
L
S
Y
L
S
D
P
R
Frog
Xenopus laevis
NP_001079545
925
103654
E795
D
P
P
K
L
N
G
E
T
Y
F
S
D
P
R
Zebra Danio
Brachydanio rerio
NP_958476
896
98728
D758
D
G
P
E
F
N
G
D
I
S
L
T
D
P
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188203
734
80915
S623
K
R
P
I
E
E
R
S
S
P
G
T
Q
Y
D
Poplar Tree
Populus trichocarpa
XP_002321013
915
101109
A784
I
I
R
K
N
G
F
A
L
E
E
D
P
H
A
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.4
86.2
83.6
N.A.
22.3
73.7
N.A.
35.9
58.3
50.7
46.1
N.A.
N.A.
N.A.
N.A.
28.3
Protein Similarity:
100
87.7
87.7
92.6
N.A.
41.6
86
N.A.
50.7
74.6
69
64.6
N.A.
N.A.
N.A.
N.A.
45.8
P-Site Identity:
100
100
0
100
N.A.
20
53.3
N.A.
0
60
53.3
40
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
6.6
100
N.A.
46.6
66.6
N.A.
0
73.3
66.6
60
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
23.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
45.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
20
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
9
0
0
9
0
9
9
0
0
0
9
% A
% Cys:
0
0
0
0
9
0
0
0
0
0
0
9
0
0
0
% C
% Asp:
50
25
0
0
0
9
0
9
9
0
0
9
67
9
17
% D
% Glu:
9
9
9
9
9
9
0
9
0
9
9
9
0
9
0
% E
% Phe:
9
0
9
0
17
0
9
9
0
9
9
0
0
0
0
% F
% Gly:
0
9
0
17
0
9
67
0
0
0
9
9
0
0
0
% G
% His:
0
9
9
0
0
0
0
0
0
0
0
0
0
9
0
% H
% Ile:
9
17
0
9
0
0
17
0
9
9
0
9
0
0
9
% I
% Lys:
9
0
0
17
9
9
0
9
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
9
17
0
0
9
17
0
50
0
0
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
9
0
9
34
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
9
25
0
0
0
0
9
0
9
9
0
17
59
0
% P
% Gln:
0
0
34
0
0
0
0
0
0
0
0
0
9
0
0
% Q
% Arg:
0
9
9
42
0
9
9
0
9
0
0
0
0
0
59
% R
% Ser:
0
0
0
0
0
25
0
42
17
9
0
42
0
9
0
% S
% Thr:
9
0
0
0
0
0
0
0
34
0
0
17
0
0
0
% T
% Val:
9
0
0
0
0
0
0
0
9
0
9
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
25
0
0
0
0
50
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _